Genipin Derivatives Protect RGC-5 from Sodium Nitroprusside-Induced Nitrosative Stress
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منابع مشابه
Genipin Derivatives Protect RGC-5 from Sodium Nitroprusside-Induced Nitrosative Stress
CHR20 and CHR21 are a pair of stable diastereoisomers derived from genipin. These stereoisomers are activators of neuronal nitric oxide synthase (nNOS) and endothelial nitric oxide synthase (eNOS). In the rat retinal ganglion (RGC-5) cell model these compounds are non-toxic. Treatment of RGC-5 with 750 μM of sodium nitroprusside (SNP) produces nitrosative stress. Both genipin derivatives, howev...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2016
ISSN: 1422-0067
DOI: 10.3390/ijms17010117